منابع مشابه
Prostate PDT dosimetry.
We provide a review of the current state of dosimetry in prostate photodynamic therapy (PDT). PDT of the human prostate has been performed with a number of different photosensitizers and with a variety of dosimetry schemes. The simplest clinical light dose prescription is to quantify the total light energy emitted per length (J/cm) of cylindrical diffusing fibers (CDF) for patients treated with...
متن کاملIn vivo PDT dosimetry: singlet oxygen emission and photosensitizer fluorescence
Photodynamic therapy (PDT) is a light activated chemotherapy that is dependent on three parameters: photosensitizer (PS) concentration; oxygen concentration; and light dosage. Due to highly variable treatment response, the development of an accurate dosimeter to optimize PDT treatment outcome is an important requirement for practical applications. Singlet oxygen is an active species in PDT, and...
متن کاملPhotodynamic Therapy (PDT): PDT Mechanisms
Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how t...
متن کاملUltrasound–fluoroscopy registration for prostate brachytherapy dosimetry
Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA b School of Computing, Queen’s University, Kingston, ON, Canada Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, School of Medicine, Baltimore, MD, USA Chair for Computer Aided Medical Procedures & Augmented Reality, Technische Universität München, Germany ...
متن کاملA dynamic dosimetry system for prostate brachytherapy
The lack of dynamic dosimetry tools for permanent prostate brachytherapy causes otherwise avoidable problems in prostate cancer patient care. The goal of this work is to satisfy this need in a readily adoptable manner. Using the ubiquitous ultrasound scanner and mobile non-isocentric C-arm, we show that dynamic dosimetry is now possible with only the addition of an arbitrarily configured marker...
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ژورنال
عنوان ژورنال: Photodiagnosis and Photodynamic Therapy
سال: 2006
ISSN: 1572-1000
DOI: 10.1016/j.pdpdt.2006.08.002